When American brothers Todd and Jan Wolfhouse travel to Germany to spread their grandfather's ashes at Oktoberfest, they stumble upon a super-secret, centuries old, underground beer games competition – "Beerfest," the secret Olympics of beer drinking. The brothers receive a less than warm welcome from their German cousins, the Von Wolfhausens, who humiliate Todd and Jan, slander their relatives, and finally cast them out of the event. Vowing to return in a year to defend their country and their family's honor, the Wolfhouse boys assemble a ragtag dream team of beer drinkers and gamers: Barry Badrinath, the consummate skills player with a dark past; Phil Krundle (aka Landfill), a one-man chugging machine; and Charlie "Fink" Finklestein, the lab tech with a PhD in All Things Beer.

This Magnificent Five train relentlessly, using their hearts, minds and livers to drink faster, smarter and harder than they ever have before. But first they must battle their own demons... as well as a bunch of big blond German jerks who want to destroy the team before they can even make it back to Munich.